Small molecules

Cat. #158380

Cat. #159958

Application: The inventors have demonstrated its radical scavenging and antiproliferative effects on three widely used and commercially available cell lines: MCF7, MDA-MB-468, MDA-MB-231.

Cat. #160531

Sub-type: Inhibitor

Application: In Malgorzata-Miller et al Sci. Rep. 6, 34221; doi: 10.1038/srep34221 (2016): Wild type mice were injected intraperitoneally (i.p.) with either PBS, or B. quintana LPS 100 μg/mouse. After 30 minutes 10 mice of each group were injected with PBS and 10 mice were injected i.p. E. coli LPS 1 μg per mouse (Escherichia coli LPS 055:B5 Sigma Chemical Co., St Louis, MI, USA) + D-galactosamine 14 mg per mouse. Survival of all 4 groups (PBS + PBS, B. quintana LPS + PBS, PBS + E. coli LPS/D-galactosamine and B. quintana LPS + E. coli LPS/D-galactosamine was assessed for 10 days.

Cat. #160829

Sub-type: Inhibitor

Application: good bioavailability F (i.p.) = 48 % and brain penetrant. good cellular penetration