F-VH032 small molecule (tool compound)

– These iBodiesÂŽ consist of an N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer decorated with low-molecular-weight compounds that function as targeting ligand (e.g., enzyme inhibitors, receptor ligands), affinity anchor (e.g., biotin) and/or imaging probe (various fluorophores).

Contributors

Inventor Institute
Alessio Ciulli ; Andrea Testa University of Dundee
Product description: – These iBodiesÂŽ consist of an N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer decorated with low-molecular-weight compounds that function as targeting ligand (e.g., enzyme inhibitors, receptor ligands), affinity anchor (e.g., biotin) and/or imaging probe (various fluorophores).
References:

Zoppi et al. 2019. J Med Chem. 62(2):699-726. PMID: 30540463.

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