Cat. #162162
Recombinant Human PSGL1 Protein
Cat. #: 162162
Availability: Please enquire for quantities and pricing
Target: PSGL1-Fc. Human P-selectin glycoprotein ligand 1 isoform 1 precursor (aka CD162)
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Geraldine Mulley; Ian Jones
Institute: University of Reading
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: Recombinant Human PSGL1 Protein
- Research fields: Cell biology
- Source: Human
- Target: PSGL1-Fc. Human P-selectin glycoprotein ligand 1 isoform 1 precursor (aka CD162)
- Description: Recombinant human PSGL1-Fc protein also known as CD162. Residues 35-326 fused to the Fc region of Human IgG1 and tagged at the C-terminus. Purified from the supernatant by a combination of lectin chromatography and IMAC.
- Tag: Terminal 6xHis
- Expression system: Insect
- Uniprot id: Q14242
Handling
- Purity: >90%
- Storage conditions: -20°C or less
- Storage buffer: PBS, 5% glycerol
- Shipping conditions: Frozen
Target Details
- Target: PSGL1-Fc. Human P-selectin glycoprotein ligand 1 isoform 1 precursor (aka CD162)
- Target background: A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Believed to be critical for the initial leukocyte capture. In microbial infection, it is believed to act as a receptor for enterovirus 71.
