#160443

UM-UC-14 (Human transitional cell carcinoma of the renal pelvis) cell line

Cat. #160443

UM-UC-14 (Human transitional cell carcinoma of the renal pelvis) cell line

Cat. #: 160443

Unit size: 1x10^6 cells / vial

Availability: 10-12 weeks

Organism: Human

Tissue: Bladder

Disease: Cancer

Model: Tumourigenic cell line

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: H. Grossman ; Anita Sabichi

Institute: University of Michigan

Tool Details
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: UM-UC-14 (Human transitional cell carcinoma of the renal pelvis) cell line
  • Alternate name: UM-UC-14; UMUC-14; UM-UC14; UMUC14; University of Michigan-Urothelial Carcinoma-14
  • Cancer: Genitourinary cancer
  • Cancers detailed: Human bladder transitional cell carcinoma
  • Research fields: Cancer
  • Organism: Human
  • Tissue: Bladder
  • Disease: Cancer
  • Growth properties: Adherent
  • Model: Tumourigenic cell line
  • Conditional: Yes
  • Description: UM-UC-14 are a human transitional cell carcinoma of the renal pelvis. These cells were assessed for their susceptibility to adenoviral mediated gene delivery, tumour growth in nude mice and differences in genetic alterations. Tumorigenicity studies in nude mice revealed the UM-UC-14 produced tumours, 1-1.5 cm in diameter in < 3 weeks. This cell line demonstrated efficient gene transduction via an adenoviral vector when compared to several of the other cells evaluated. UM-UC-14 also demonstrated one of the highest levels of Coxsackie adenovirus receptor expression of the cells tested. These assays allowed for characterization of some of the most important features in each of the respective lines in an effort to more accurately establish commonly observed phenomena across cells of the same type of neoplasm.

Handling

  • Format: Frozen
  • Growth medium: Cells were grown in Dulbecco's modified Eagle's medium (DMEM) containing 10% heat inactivated Foetal Bovine Serum (FBS) and were supplemented with 1% penicillin and streptomycin at 37°C in 5% CO2 environment.
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice

Related Tools

  • Related tools: UM-UC-1 (Human bladder transitional cell carcinoma) cell line ; UM-UC-3 (Human bladder transitional cell carcinoma) cell line ; UM-UC-4 (Human adenocarcinoma lymph node metastasis) cell line ; UM-UC-5 (Human squamous cell carcinoma of the bladder) cell line ; UM-UC-7 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-9 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-10 (Human transitional cell carcinoma of the bladder) cell line

References

  • Sabichi et al. 2006. J Urol. 175(3 Pt 1):1133-7. PMID: 16469639.
  • Grossman et al. 1984. J Urol. 132(4):834-7. PMID: 6471236.