#162288

STUB1 (CHIP) KO H1299 cell line

Cat. #162288

STUB1 (CHIP) KO H1299 cell line

Cat. #: 162288

Organism: Human

Tissue: Lung

Disease: Cancer

Model: Transgenic (KO)

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Petr Muller

Institute: Masaryk Memorial Cancer Institute

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: STUB1 (CHIP) KO H1299 cell line
  • Parental cell: H1299
  • Organism: Human
  • Gender: Male
  • Tissue: Lung
  • Donor: 43 years old, white
  • Disease: Cancer
  • Morphology: Epithelial
  • Growth properties: Adherent
  • Model: Transgenic (KO)
  • Model description: CRISPR Cas9 abolished expression of STIP1 homology and U-Box containing protein 1 (STUB)
  • Crispr: Yes
  • Conditional: No
  • Description: H1299 cell line derivative with abolished expression of STIP1 homology and U-Box containing protein 1 (STUB1), coding for C terminus of HSC70-Interacting Protein (CHIP)
  • Application: Cell culture
  • Biosafety level: BSL-2

Target Details

  • Target: STIP1 homology and U-Box containing protein 1 (STUB1)
  • Target background: gene coding for Carboxy-terminus of Hsc70-interacting protein (CHIP), which functions as a co-chaperone and ubiquitin E3 ligase in protein degradation

Applications

  • Application: Cell culture

Handling

  • Format: Frozen
  • Atmosphere: humidified CO2 atmosphere
  • Storage conditions: Liquid Nitrogen
  • Cultured in antibiotics: Yes, penicillin/streptomycin

References

  • Unpublished