#157674

P815.Trh4 cell line

Cat. #157674

P815.Trh4 cell line

Cat. #: 157674

Sub-type: Continuous

Unit size: 1x10^6 cells / vial

Availability: 3-4 weeks

Organism: Mouse

Tissue: Bone Marrow

Disease: Cancer

Model: Tumour line

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Thorbald Van Hall

Institute: Leiden University and Leiden University Medical Center; Stichting Oncode Institute

Tool Details
Target Details
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: P815.Trh4 cell line
  • Cancers detailed: Mouse mast cell neoplasm
  • Research fields: Cancer
  • Tool sub type: Continuous
  • Parental cell: P815
  • Organism: Mouse
  • Tissue: Bone Marrow
  • Disease: Cancer
  • Model: Tumour line
  • Description: This cell line provides a model to help to understand T-cell recognition through Trh4 expression. ER-resident ceramide synthase Trh4 is a prototypic example of a neo-antigen selectively presented by cells through various pathways. The P815 cell line has been made to over-express Trh4 and can be utilised to understand this peptide presentation process.
  • Production details: Retroviral transduction of the mouse Trh4 gene in an IRES-GFP construct
  • Biosafety level: 1
  • Cellosaurus id: CVCL_2154

Target Details

  • Target: Trh4

Handling

  • Format: Frozen
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice
  • Storage conditions: Liquid Nitrogen
  • Mycoplasma free: Yes

References

  • Oliveira et al. 2011. Eur J Immunol. 41(11):3114-24. PMID: 21898382.