Melb-m5 cell line

Immortal melanoblast cell line irreversibly differentiated from immortal murine neural crest-like stem cells which were derived from Dock7m/Dock7m C57BL6/J mice

Contributors

Inventor Institute
Elena Sviderskaya St. George's University London
Cat. #: 162048
Organism: Mouse
Tissue: Skin
Model: Immortalised non-cancerous cell lines
Morphology: Small, oval-fusiform
Product description: The melb-m5 line is an immortal melanoblast cell line irreversibly differentiated from immortal murine neural crest-like stem cells which were derived from Dock7m/Dock7m C57BL6/J mice. This melanoblast line may be useful for developmental studies and, as melanoblasts display mechanisms similar to tumour cells (migration to and invasion of the epidermis) they may be a useful tool in studies of melanoma development.
Storage conditions: liquid N2
Growth medium: RPMI + FBS (10%) + fibroblast growth factor 2 (FGF2) (40 pM) + mouse stem cell factor (mSCF) (20 ng/ml)

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