#154032

Human Imatinib Mesylate-Resistant Leukaemia Cell Line

Cat. #154032

Human Imatinib Mesylate-Resistant Leukaemia Cell Line

Cat. #: 154032

Sub-type: Continuous

Unit size: 1x10^6 cells / vial

Organism: Human

Disease: Cancer

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Steven Grant

Institute: Virginia Commonwealth University

Tool Details
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Human Imatinib Mesylate-Resistant Leukaemia Cell Line
  • Cancer: Blood cancer
  • Cancers detailed: Acute Lymphoblastic Leukemia (Ph+ ALL);Chronic Myelogenous Leukemia (CML)
  • Research fields: Cancer
  • Tool sub type: Continuous
  • Parental cell: BV173
  • Organism: Human
  • Disease: Cancer
  • Description: The human ALL cell line, named BV173, was altered to be imatinib resistant and contains the most frequently observed mutation (E255K) responsible for drug resistance in patients.

Handling

  • Format: Frozen
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice

References

  • Cormack et al. 1992. J Mol Biol. 228(4):1078-90. PMID: 1474579.
  • Structural requirements for the processing of Escherichia coli 5 S ribosomal RNA by RNase E in vitro.