HSF1 and HSF2 KO H1299 cell line

H1299 cell line derivative with CRISPR Cas9 abolished expression of Heat Shock Transcription Factor 1 (HSF1) and Heat Shock Transcription Factor 2 (HSF2) used to study the roles of HSF1 and HSF2 in a stress response context

Contributors

Inventor Institute
Petr Muller Masaryk Memorial Cancer Institute
Cat. #: 162287
Cancer types: Lung cancer
Organism: Human
Tissue: Lung
Gender: Male
Model: Transgenic (KO)
Morphology: Epithelial
Growth properties: Adherent
Primary citation: Simoncik et al., 2024 PLoS ONE 19(11): e0312524
Product description: H1299 cell line derivative with CRISPR Cas9 abolished expression of Heat Shock Transcription Factor 1 (HSF1) and Heat Shock Transcription Factor 2 (HSF2) used to study the roles of HSF1 and HSF2 in a stress response context
Gender: Male
CRISPR: Yes
Parental cell line: H1299
Model description: CRISPR Cas9 abolished expression of Heat Shock Transcription Factor 1 (HSF1) and Heat Shock Transcription Factor 2 (HSF2)
Disease: Cancer
Format: Frozen
Storage conditions: Liquid Nitrogen
Atmosphere: humidified CO2 atmosphere
References:

Simoncik et al., 2024 PLoS ONE 19(11): e0312524

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