ENO 1 F423A M2 HAP1 cell line

Chronic myelogenous leukaemia cell line with mutated F423A in the ENO1 glycolytic enzyme (clone M2)

Contributors

Inventor Institute
Marit Otterlei Norwegian University of Science and Technology
Cat. #: 162181
Organism: Human
Tissue: Bone marrow
Gender: Male
Model: Genetically modified cell line; knock-in
Morphology: Fibroblast-like
Growth properties: Adherent
Product description: Chronic myelogenous leukaemia cell line with mutated PCNA interacting domain APIM (F423A) in the ?-Enolase (ENO1) glycolytic enzyme (clone M2)
Gender: Male
CRISPR: Yes
Parental cell line: HAP1
Model description: mutated PCNA interacting domain APIM (F423A) in the ENO1 gene
disease: Membranous glomerulonephritis
Products or characteristics of interest: near-haploid cell line containing half of the usual number of chromosomes
Storage conditions: Liquid Nitrogen
Shipping conditions: Dry ice
Subculture routine: Cells should be kept at maximum 75% confluency
Atmosphere: 5% CO2

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