#161794

C3.1 cell line

Cat. #161794

C3.1 cell line

Cat. #: 161794

Organism: Human

Tissue: Skin

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Christoper Stipp

Institute: University Of Iowa Research Foundation

Primary Citation: Feddersen et al.2019. Cancer Res. 79(19). PMID: 31416846

Tool Details
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: C3.1 cell line
  • Alternate name: C3.1
  • Parental cell: A375 Melanoma (ATCC)
  • Organism: Human
  • Gender: Female
  • Tissue: Skin
  • Donor: A375 (ATCC) -human melanoma cell line of a solid tumor from a 54-year-old female.
  • Morphology: Compact Morphology
  • Description: Spontaneous vemurafenib resistant A375 Melanoma Clones. Shows frequent alterations of BRAF^V600 protein. No increased VAV1 protein levels.
  • Production details: Long-term cultures of A375 cells in 3 ?M vemurafenib. Spontaneous vemurafenib-resistant clones and populations were created after 2–3 and 4–6 weeks cultured in 3 mm vemurafenib. Maintained in media with 3 mm vemurafenib.

Handling

  • Growth medium: DMEM(Gibco) suplemented with penicillin/streptomycin (Gibco) and 10% FBS (Gibco).

References

  • Feddersen et al.2019. Cancer Res. 79(19).PMID: 31416844
  • Zhu et al. 2022. npj Precis. Onc. PMID: 36271144