#153869

Anti-Tumor Necrosis Factor (TNF-a) [12F6]

Please Enter Your Email ID
Email ID

Cat. #153869

Anti-Tumor Necrosis Factor (TNF-a) [12F6]

Cat. #: 153869

Sub-type: Primary antibody

Unit size: 100 ug

Target: Tumor Necrosis Factor- alpha

Class: Monoclonal

Application: ELISA ; IP ; WB

Reactivity: Horse

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Royal McGraw

Institute: University of Georgia

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Tumor Necrosis Factor (TNF-a) [12F6]
  • Alternate name: TNF-?
  • Research fields: Apoptosis and autophagy;Cell signaling and signal transduction
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Horse
  • Host: Mouse
  • Application: ELISA ; IP ; WB
  • Description: Tumor necrosis factor is a cell signaling protein or cytokine that is involved in inflammation, and specifically one of the proteins in the acute phase reaction. TNF is produced mainly by macrophages but other white cells too. Some of its roles are to induce fever, apoptotic cell death, inhibit tumorigenesis and inflammation. Diseases associated with dysregulation of TNF production include inflammatory bowel disease (IBD), Psoriasis, Alzheimer's and cancer.
  • Immunogen: Protein
  • Isotype: IgG2b

Target Details

  • Target: Tumor Necrosis Factor- alpha
  • Target background: Tumor necrosis factor is a cell signaling protein or cytokine that is involved in inflammation, and specifically one of the proteins in the acute phase reaction. TNF is produced mainly by macrophages but other white cells too. Some of its roles are to induce fever, apoptotic cell death, inhibit tumorigenesis and inflammation. Diseases associated with dysregulation of TNF production include inflammatory bowel disease (IBD), Psoriasis, Alzheimer's and cancer.

Applications

  • Application: ELISA ; IP ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Su et al. 1992. Hybridoma. 11(6):715-27. PMID: 1284121.
  • Equine tumor necrosis factor alpha: cloning and expression in Escherichia coli, generation of monoclonal antibodies, and development of a sensitive enzyme-linked immunosorbent assay.