Cat. #156435
Anti-Pirt
Cat. #: 156435
Unit size: 100 ug
Target: phosphoinositide interacting regulator of TRP (Pirt)
Class: Polyclonal
Application: IHC
Reactivity: Human
Host: Rabbit
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Johns Hopkins University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Pirt
- Research fields: Cell signaling and signal transduction
- Class: Polyclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Rabbit
- Application: IHC
- Description: Transient receptor potential vanilloid 1 (TRPV1) is a molecular sensor of pain. Its channel activity can be modulated by several mechanisms. Phosphoinositide interacting regulator of TRP (Pirt), a membrane protein, expressed specifically in the peripheral nervous system (PNS), predominantly in nociceptive (pain) neurons has been described by several experiments indicating that Pirt is a key component of the TRPV1 complex and positively regulates TRPV1 activity. To further study this signaling pathway, a rabbit polyclonal anti-Pirt antibody that recognizes the Pirt protein has been developed.
Target Details
- Target: phosphoinositide interacting regulator of TRP (Pirt)
- Target background: Transient receptor potential vanilloid 1 (TRPV1) is a molecular sensor of pain. Its channel activity can be modulated by several mechanisms. Phosphoinositide interacting regulator of TRP (Pirt), a membrane protein, expressed specifically in the peripheral nervous system (PNS), predominantly in nociceptive (pain) neurons has been described by several experiments indicating that Pirt is a key component of the TRPV1 complex and positively regulates TRPV1 activity. To further study this signaling pathway, a rabbit polyclonal anti-Pirt antibody that recognizes the Pirt protein has been developed.
Applications
- Application: IHC
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Kim et al. 2008. Cell. 133(3):475-85. PMID: 18455988.
