#152640

Anti-mib [6B2]

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Cat. #152640

Anti-mib [6B2]

Cat. #: 152640

Unit size: 100 ug

Target: mind bomb

Class: Monoclonal

Application: WB

Reactivity: Zebrafish

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: A*STAR Accelerate Technologies Pte Ltd

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-mib [6B2]
  • Research fields: Other
  • Clone: 6B2
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Zebrafish
  • Host: Mouse
  • Application: WB
  • Description: Zebrafish mind bomb (mib) was isolated in a large-scale screen aiming for morphologically discernible phenotypes. Mib mutants have phenotypes similar to Notch pathway mutants: a dramatic increase of primary neurons and somatic segmentation abnormalities. mib was positional cloned to be a novel gene. Mib is a novel E3 ligase with three Ring Finger (RF) domains in the C-terminal. Mib can interact with Delta, a Notch ligand. The interaction will mediate a RF-dependent ubiquitination and endocyto...
  • Immunogen: GST fusion-Fish mib protein
  • Isotype: IgG2b
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: Zebrafish

Target Details

  • Target: mind bomb
  • Target background: Zebrafish mind bomb (mib) was isolated in a large-scale screen aiming for morphologically discernible phenotypes. Mib mutants have phenotypes similar to Notch pathway mutants: a dramatic increase of primary neurons and somatic segmentation abnormalities. mib was positional cloned to be a novel gene. Mib is a novel E3 ligase with three Ring Finger (RF) domains in the C-terminal. Mib can interact with Delta, a Notch ligand. The interaction will mediate a RF-dependent ubiquitination and endocyto...

Applications

  • Application: WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C