Cat. #161584
Anti-Maspin [16F7]
Cat. #: 161584
Sub-type: Primary antibody
Availability: 3-4 weeks
Target: SERPINB5, Maspin
Class: Monoclonal
Application: WB, IF, IP, IHC
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Phillip Bird
Institute: Monash University
Primary Citation: Teoh SSY et al. 2012. Hybridoma. 31(5):333-9. PMC3482377.
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Maspin [16F7]
- Alternate name: Anti-SERPINB5
- Cancer: Breast cancer;Genitourinary cancer
- Cancers detailed: Breast cancer;Prostate
- Research fields: Cancer
- Clone: 16F7
- Tool sub type: Primary antibody
- Class: Monoclonal
- Molecular weight: 42 kDa
- Reactivity: Human
- Host: Mouse
- Disease: Breast Cancer
- Application: WB, IF, IP, IHC
- Description: Maspin is a SERPIN family protein and has been associated with the inhibition of tumor growth and invasion. As of yet, the function of Maspin is unclear. This mouse monoclonal antibody recognizes human Maspin protein in its native and denatured forms, compared to other commercially available antibodies which do not recognize Maspin's denatured form. This antibody can be used in a more expansive range of analytical techniques to study its function and may be helpful in identifying other protei...
- Immunogen: full length recombinant Maspin
- Isotype: IgG2a
- Recommended controls: SERPINB5, Maspin
Target Details
- Target: SERPINB5, Maspin
- Target alternate names: SERPINB5, serpin family B member 5, PI5, Serpin B5, PI-5, maspin peptidase inhibitor 5, protease inhibitor 5
- Molecular weight: 42 kDa
- Target background: Maspin is a member of the serine protease inhibitor family (Serpins) and is encoded by SERPINB4. It is a 42 kDa, non-inhibitory protein. It is proposed as a tumor suppressor gene and has been suggested to inhibit tumor growth and migration, although this is controversial. Maspin expression has been found to correlate with prognosis for breast and prostate cancers.
Applications
- Application: WB, IF, IP, IHC
Handling
- Storage buffer: PBS with 0.02% sodium azide
- Storage conditions: Long term store at -20° C. Short term store at 4° C
- Shipping conditions: shipment at -20° C
References
- Teoh SSY et al. 2012. Hybridoma. 31(5):333-9. PMC3482377.
