Cat. #153747
Anti-Integrin Beta 3a (GPIIIa, CD61) [AP-5]
Cat. #: 153747
Unit size: 100 ug
Target: Integrin Beta 3a (GPIIIa, CD61)ÄÂĂÂ
Class: Monoclonal
Application: FACS ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Richard Aster
Institute: Versiti Blood Research Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Integrin Beta 3a (GPIIIa, CD61) [AP-5]
- Alternate name: CD-61
- Research fields: Immunology
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: ~ 86-87 kDa
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; WB
- Description: Glycoprotein IIb/IIIa, also known as integrin aIIb?ĂÂ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
- Immunogen: peptide
- Isotype: IgG1
Target Details
- Target: Integrin Beta 3a (GPIIIa, CD61)ÄÂĂÂ
- Molecular weight: ~ 86-87 kDa
- Target background: Glycoprotein IIb/IIIa, also known as integrin aIIb?ĂÂ3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
Applications
- Application: FACS ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Honda et al. 1995. J Biol Chem. 270(20):11947-54. PMID: 7538128.
- Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit.
