Cat. #151533
Anti-Factor VII [RFF-VII/1]
Cat. #: 151533
Unit size: 100 ug
Availability: 3-4 weeks
Target: Factor VII
Class: Monoclonal
Application: ELISA ; Fn ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Alison Goodall
Institute: University College London (UCL)
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Factor VII [RFF-VII/1]
- Research fields: Tissue-specific biology
- Clone: RFF-VII/1
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; Fn ; WB
- Description: Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa via cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin. This monoclonal antibody partially inhibits human Factor VII activity.
- Immunogen: Purified human factor VII
- Isotype: IgG1 kappa
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Factor VII
- Target background: Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa via cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin. This monoclonal antibody partially inhibits human Factor VII activity.
Applications
- Application: ELISA ; Fn ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Takase et al. 1988. J Clin Pathol. 41(3):342-5. PMID: 3360958.
- Takase et al. 1988. J Clin Pathol. 41(3):337-41. PMID: 3360957.
- Monoclonal antibodies to human factor VII: production of immunodepleted plasma for VII:C assays.
- Monoclonal antibodies to human factor VII: a one step immunoradiometric assay for VII:Ag.
