Cat. #152659
Anti-CXCL16 [4.4]
Cat. #: 152659
Unit size: 100 ug
Availability: 3-4 weeks
Target: C-X-C motif chemokine 16
Class: Monoclonal
Application: IF ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: A*STAR Accelerate Technologies Pte Ltd
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CXCL16 [4.4]
- Research fields: Immunology;Tissue-specific biology
- Clone: 4.4
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IF ; WB
- Description: CXCL16, a newly discovered CXC chemokine, exists both in a transmembrane and a soluble form. The membrane bound chemokine act as a ligand for CXC chemokine receptor (CXCR) 6 which is expressed by peripheral blood leukocytes. This membrane-bound CXCL16 is expressed in antigen-presenting cells such as monocytes, macrophages, B cells and dendritic cells in the T-cell zone of lymph nodes, whereas the soluble CXCL16 can be produced by constitutive cleavage from the cell membrane. In addition, CXCL16 expression has been associated with a number of human inflammatory diseases including rheumatoid arthritis, interstitial lung diseases, atherosclerosis, coronary artery disease and liver injury.
- Immunogen: GST-CXCL16 (143-224aa) fusion protein
- Isotype: IgG1 kappa
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: C-X-C motif chemokine 16
- Target background: CXCL16, a newly discovered CXC chemokine, exists both in a transmembrane and a soluble form. The membrane bound chemokine act as a ligand for CXC chemokine receptor (CXCR) 6 which is expressed by peripheral blood leukocytes. This membrane-bound CXCL16 is expressed in antigen-presenting cells such as monocytes, macrophages, B cells and dendritic cells in the T-cell zone of lymph nodes, whereas the soluble CXCL16 can be produced by constitutive cleavage from the cell membrane. In addition, CXCL16 expression has been associated with a number of human inflammatory diseases including rheumatoid arthritis, interstitial lung diseases, atherosclerosis, coronary artery disease and liver injury.
Applications
- Application: IF ; WB
Handling
- Format: Liquid
- Concentration: 1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
