CXCL16, a newly discovered CXC chemokine, exists both in a transmembrane and a soluble form. The membrane bound chemokine act as a ligand for CXC chemokine receptor (CXCR) 6 which is expressed by peripheral blood leukocytes. This membrane-bound CXCL16 is expressed in antigen-presenting cells such as monocytes, macrophages, B cells and dendritic cells in the […]
| Institute |
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| A*STAR Accelerate Technologies Pte Ltd |
| Cat. #: | 152659 |
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| Unit size: | 100 ug |
| Research Fields: | Immunology;Tissue-specific biology |
| Application: | IF ; WB |
| Target: | C-X-C motif chemokine 16 |
| Reactivity: | Human |
| Clone: | 4.4 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | CXCL16, a newly discovered CXC chemokine, exists both in a transmembrane and a soluble form. The membrane bound chemokine act as a ligand for CXC chemokine receptor (CXCR) 6 which is expressed by peripheral blood leukocytes. This membrane-bound CXCL16 is expressed in antigen-presenting cells such as monocytes, macrophages, B cells and dendritic cells in the T-cell zone of lymph nodes, whereas the soluble CXCL16 can be produced by constitutive cleavage from the cell membrane. In addition, CXCL16 expression has been associated with a number of human inflammatory diseases including rheumatoid arthritis, interstitial lung diseases, atherosclerosis, coronary artery disease and liver injury. |
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| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | GST-CXCL16 (143-224aa) fusion protein |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | CXCL16, a newly discovered CXC chemokine, exists both in a transmembrane and a soluble form. The membrane bound chemokine act as a ligand for CXC chemokine receptor (CXCR) 6 which is expressed by peripheral blood leukocytes. This membrane-bound CXCL16 is expressed in antigen-presenting cells such as monocytes, macrophages, B cells and dendritic cells in the T-cell zone of lymph nodes, whereas the soluble CXCL16 can be produced by constitutive cleavage from the cell membrane. In addition, CXCL16 expression has been associated with a number of human inflammatory diseases including rheumatoid arthritis, interstitial lung diseases, atherosclerosis, coronary artery disease and liver injury. |
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| Format: | Liquid |
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| Concentration: | 1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151016 | Anti-CyclinA [E72.1] |
Key Info
Anti-CyclinA [E72.1]
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| 151021 | Anti-CyclinB1 [V152] |
Key Info
Anti-CyclinB1 [V152]
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| 151034 | Anti-HSVUL42 [13D11] |
Key Info
Anti-HSVUL42 [13D11]
|
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| 151036 | Anti-ICAM1 [15.2] |
Key Info
Anti-ICAM1 [15.2]
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| 151039 | Anti-Integrin aVb3 [23C6] |
Key Info
Anti-Integrin aVb3 [23C6]
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