Anti-CLEC16A [4F11]

Antibody against CLEC16A (specifically binds to C-terminal human peptide CLEC16A954-980: VIVNETEADSKPSKNVARSAAVETASL) CLEC16A is a cytosolic protein which is differentially expressed in human immune cells and is known to be highly expressed on B-lymphocytes, natural killer (NK) and dendritic cells. CLEC16A gene has been linked to several autoimmune diseases, including Addison’s disease, diabetes melllitus, Crohn’s disease, […]

Contributors

Institute
The University of British Columbia
Cat. #: 157893
Unit size: 100 ug
Research Fields: Disease (not cancer);Immunology;Neurobiology
Application: ELISA ; WB
Target: C-Type Lectin Domain Containing 16A
Reactivity: Human
Class: Monoclonal
Alternate name: CLEC16A (also known as KIAA35)
Product description: Antibody against CLEC16A (specifically binds to C-terminal human peptide CLEC16A954-980: VIVNETEADSKPSKNVARSAAVETASL) CLEC16A is a cytosolic protein which is differentially expressed in human immune cells and is known to be highly expressed on B-lymphocytes, natural killer (NK) and dendritic cells. CLEC16A gene has been linked to several autoimmune diseases, including Addison's disease, diabetes melllitus, Crohn's disease, primary biliary cirrhosis, juvenile idiopathic arthritis, rheumatoid arthritis and multiple sclerosis. . CLEC16A has been shown to regulate various immune pathways including directly regulating leukocyte antigen class II pathway in antigen presenting cells, autophagy, mitophagy, and NK cell cytotoxicity.
Conjugation: Unconjugated
Immunogen: 27-mer C-terminal human peptide (CLEC16A 954-980: VIVNETEADSKPSKNVARSAAVETASL) linked to KLH
Target background: antibody against CLEC16A (specifically binds to C-terminal human peptide CLEC16A954-980: VIVNETEADSKPSKNVARSAAVETASL) CLEC16A is a cytosolic protein which is differentially expressed in human immune cells and is known to be highly expressed on B-lymphocytes, natural killer (NK) and dendritic cells. CLEC16A gene has been linked to several autoimmune diseases, including Addison's disease, diabetes melllitus, Crohn's disease, primary biliary cirrhosis, juvenile idiopathic arthritis, rheumatoid arthritis and multiple sclerosis. . CLEC16A has been shown to regulate various immune pathways including directly regulating leukocyte antigen class II pathway in antigen presenting cells, autophagy, mitophagy, and NK cell cytotoxicity.
Format: Liquid
Shipping conditions: Dry ice
References:

van Luijn et al. 2015. Brain. 138(Pt 6):1531-47. PMID: 25823473.

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