The ITGA5 gene encodes the integrin alpha 5 chain.
| Inventor | Institute |
|---|---|
| Arnoud Sonnenberg | Netherlands Cancer Institute |
| Cat. #: | 154737 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology;Cell signaling and signal transduction |
| Application: | FACS ; IHC ; IP |
| Target: | CD49E |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | ITGA5 |
|---|---|
| Product description: | The ITGA5 gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Molecular weight: | 135 kDa |
| Immunogen: | U 937 cells |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | The ITGA5 gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Sopp et al. 1997. Vet Immunol Immunopathol. 56(1-2):11-25. PMID: 9220577. te Velde et al. 1988. J Immunol. 140(5):1548-54. PMID: 3279117. |
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