Cat. #153172
Anti-CD45RA [BU77]
Cat. #: 153172
Sub-type: Primary antibody
Unit size: 100 ug
Target: Protein tyrosine phosphatase receptor type C
Class: Monoclonal
Application: FACS ; IHC
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Roy Jefferis
Institute: University of Birmingham
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD45RA [BU77]
- Alternate name: PTPRC, CD45RA
- Cancer: Blood cancer
- Cancers detailed: Leukemia
- Research fields: Cell biology;Immunology;Stem cell biology
- Clone: BU77
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC
- Description: CD45RA is a transmembrane tyrosine phosphatase that is present on all leukocytes. CD45 RA regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45 can be expressed as one of several isoforms by alternative splicing of exons that comprise the extracellular domain. CD45RA is expressed on na??ve T cells, as well as the effector cells in both CD4 and CD8. CD45RA is an isoform of the PTPRC complex which is sel...
- Immunogen: Perpheral Blood B cells
- Isotype: IgG2a
- Myeloma used: P3X63Ag8.653
Target Details
- Target: Protein tyrosine phosphatase receptor type C
- Tissue cell line specificity: Mouse
- Target background: CD45RA is a transmembrane tyrosine phosphatase that is present on all leukocytes. CD45 RA regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45 can be expressed as one of several isoforms by alternative splicing of exons that comprise the extracellular domain. CD45RA is expressed on nave T cells, as well as the effector cells in both CD4 and CD8. CD45RA is an isoform of the PTPRC complex which is s...
Applications
- Application: FACS ; IHC
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
