Anti-CD44 [BU52]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-CD44 [BU52]
• Alternate name: CD44 Molecule; Hematopoietic Cell E- And L-Selectin Ligand; GP9 Lymphocyte Homing/Adhesion Receptor; Chondroitin Sulfate Proteoglycan 8; Extracellular Matrix Receptor III; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein; Hyaluronate Receptor; Hermes Antigen; ECMR-III; HUTCH-I; Epican; CDW44; MDU2; MDU3; MIC4; LHR; Cell Surface Glycoprotein CD44; Phagocytic Glycoprotein I; Soluble CD44; CSPG8; HCELL; PGP-1; MC56; Pgp1
• Research fields: Cancer;Cell biology;Cell signaling and signal transduction;Immunology
• Clone: BU52
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Strain: Balb/c
• Reactivity: Human
• Host: Mouse
• Application: FACS ; IHC ; IF ; IP ; WB
• Description: A broadly distributed receptor. Variants of CD44 are associated with metastasis.
• Immunogen: Hiatt myeloma cells
• Isotype: IgG1
• Myeloma used: NS0

Target Details

• Target: CD44
• Target background: A broadly distributed receptor. Variants of CD44 are associated with metastasis.

Applications

• Application: FACS ; IHC ; IF ; IP ; WB

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Dry ice

References

• Knapp W. et al. 1989. Leukocyte Typing IV Oxford University Press
• Brown et al. 2005. Exp Cell Res. 303(2):400-14. PMID: 15652352.
• Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells.
• Takahashi et al. 2003. Lung Cancer. 41(2):145-53. PMID: 12871777.
• Restoration of CD44S in non-small cell lung cancer cells enhanced their susceptibility to the macrophage cytotoxicity.
• Okamoto et al. 1999. J Biol Chem. 274(36):25525-34. PMID: 10464284.
• Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.
• Baker et al. 1998. Blood. 92(8):2830-43. PMID: 9763568.
• Prolonged phenotypic, Fn, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand.
• Guo et al. 1994. Int Immunol. 6(2):213-21. PMID: 7512372.
• Palmitoylation of CD44 interferes with CD3-mediated signaling in human T lymphocytes.
• Lesley et al. 1993. Adv Immunol. 54:271-335. PMID: 8379464.
• CD44 and its interaction with extracellular matrix.
• Anstee et al. 1991. Immunology. 74(2):197-205. PMID: 1721039.
• New monoclonal antibodies in CD44 and CD58: their use to quantify CD44 and CD58 on normal human erythrocytes and to compare the distribution of CD44 and CD58 in human tissues.