Cat. #151434
Anti-CD44 [BU52]
Cat. #: 151434
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: CD44
Class: Monoclonal
Application: FACS ; IHC ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Roy Jefferis
Institute: University of Birmingham
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD44 [BU52]
- Alternate name: CD44 Molecule; Hematopoietic Cell E- And L-Selectin Ligand; GP9 Lymphocyte Homing/Adhesion Receptor; Chondroitin Sulfate Proteoglycan 8; Extracellular Matrix Receptor III; Heparan Sulfate Proteoglycan; Phagocytic Glycoprotein; Hyaluronate Receptor; Hermes Antigen; ECMR-III; HUTCH-I; Epican; CDW44; MDU2; MDU3; MIC4; LHR; Cell Surface Glycoprotein CD44; Phagocytic Glycoprotein I; Soluble CD44; CSPG8; HCELL; PGP-1; MC56; Pgp1
- Research fields: Cancer;Cell biology;Cell signaling and signal transduction;Immunology
- Clone: BU52
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IF ; IP ; WB
- Description: A broadly distributed receptor. Variants of CD44 are associated with metastasis.
- Immunogen: Hiatt myeloma cells
- Isotype: IgG1
- Myeloma used: NS0
Target Details
- Target: CD44
- Target background: A broadly distributed receptor. Variants of CD44 are associated with metastasis.
Applications
- Application: FACS ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Knapp W. et al. 1989. Leukocyte Typing IV Oxford University Press
- Brown et al. 2005. Exp Cell Res. 303(2):400-14. PMID: 15652352.
- Regulation of hyaluronan binding by F-actin and colocalization of CD44 and phosphorylated ezrin/radixin/moesin (ERM) proteins in myeloid cells.
- Takahashi et al. 2003. Lung Cancer. 41(2):145-53. PMID: 12871777.
- Restoration of CD44S in non-small cell lung cancer cells enhanced their susceptibility to the macrophage cytotoxicity.
- Okamoto et al. 1999. J Biol Chem. 274(36):25525-34. PMID: 10464284.
- Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.
- Baker et al. 1998. Blood. 92(8):2830-43. PMID: 9763568.
- Prolonged phenotypic, Fn, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand.
- Guo et al. 1994. Int Immunol. 6(2):213-21. PMID: 7512372.
- Palmitoylation of CD44 interferes with CD3-mediated signaling in human T lymphocytes.
- Lesley et al. 1993. Adv Immunol. 54:271-335. PMID: 8379464.
- CD44 and its interaction with extracellular matrix.
- Anstee et al. 1991. Immunology. 74(2):197-205. PMID: 1721039.
- New monoclonal antibodies in CD44 and CD58: their use to quantify CD44 and CD58 on normal human erythrocytes and to compare the distribution of CD44 and CD58 in human tissues.
