CD25 associates with the IL-2 receptor ? (CD122) and common ? chains (CD132) to form the high affinity IL-2R complex.
| Institute |
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| Ludwig Institute for Cancer Research |
| Cat. #: | 152358 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Biochemistry;Immunology |
| Application: | FACS ; IHC ; IP |
| Target: | CD25 |
| Reactivity: | Mouse |
| Clone: | PC61 5.3 |
| Host: | Rat |
| Class: | Monoclonal |
| Alternate name: | Interleukin 2 Receptor Subunit Alpha; IL-2 Receptor Subunit Alpha; IL-2R Subunit Alpha; TAC Antigen; P55; Insulin-Dependent Diabetes Mellitus 1; CD25 Antigen |
|---|---|
| Product description: | CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor ÄÂ? chain. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ÄÂĂÂ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor ÄÂ? (CD122) and common ÄÂ? chains (CD132) to form the high affinity IL-2R complex. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Target background: | CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor a chain. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+T cells termed T regulatory cells. CD25 associates with the IL-2 receptor ? (CD122) and common ? chains (CD132) to form the high affinity IL-2R complex. |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Lowenthal et al. 1985. J Immunol. 135(6):3988-94. PMID: 3934270. |
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