#151525

Anti-ATG9 [Atg9 14F2 8B1]

Cat. #151525

Anti-ATG9 [Atg9 14F2 8B1]

Cat. #: 151525

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Autophagy-related protein 9 (ATG9)

Class: Monoclonal

Application: IHC ; IP ; ELISA ; IHC ; IF ; IP ; WB

Reactivity: Human ; Mouse ; Rat

Host: Hamster

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Sharon Tooze

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-ATG9 [Atg9 14F2 8B1]
  • Clone: Atg9 14F2 8B1
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 105 kDa
  • Strain: Armenian
  • Reactivity: Human ; Mouse ; Rat
  • Host: Hamster
  • Application: IHC ; IP ; ELISA ; IHC ; IF ; IP ; WB
  • Description: Autophagy is an important process associated with infectious disease, neurodegeneration, cancer and the maintenance of cellular homeostasis. ATG9 is an essential component of the autophagy machinery and is found on autophagosomes. It is a multi-spanning membrane protein which makes it useful for sub-cellular localization studies. The detection of this protein provides important information about cell health and survival.
  • Immunogen: Conserved C-terminal synthetic peptide of Human ATG9 sequence
  • Isotype: IgG
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: Endogenous protein, tagged over expressed protein and sRNA-depleted HEK 293 cells,

Target Details

  • Target: Autophagy-related protein 9 (ATG9)
  • Molecular weight: 105 kDa
  • Tissue cell line specificity: Endogenous protein, tagged over expressed protein and sRNA-depleted HEK 293 cells,
  • Target background: Autophagy is an important process associated with infectious disease, neurodegeneration, cancer and the maintenance of cellular homeostasis. ATG9 is an essential component of the autophagy machinery and is found on autophagosomes. It is a multi-spanning membrane protein which makes it useful for sub-cellular localization studies. The detection of this protein provides important information about cell health and survival.

Applications

  • Application: IHC ; IP ; ELISA ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.7 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase III?
  • Chan et al. 2009. Mol Cell Biol. 29(1):157-71. PMID: 18936157.
  • Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.
  • Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes.