#157999

Isobenzofuran analog of sclerophytin A (5a) small molecule

Cat. #157999

Isobenzofuran analog of sclerophytin A (5a) small molecule

Cat. #: 157999

Availability: Please enquire for quantities and pricing

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Matt McIntosh

Institute: University of Arkansas, Fayetteville

Tool Details
Handling
Target Details
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Tool name: Isobenzofuran analog of sclerophytin A (5a) small molecule
  • Research fields: Cancer
  • Description: Naturally occurring products 2, 11 cyclized cembranoids have been shown to inhibit the growth of KB3 nasopharyngeal carcinoma. The standard cancer cell line used to test for chemotherapy effectiveness. The bicyclic hydroisobenzofuran is the beneficial compounds that are naturally occurring in 2, 11 cyclized cembranoids. This compound has shown inhibition of growth of KB3 cancer test cells and could be used in cancer and antibiotics research.

Handling

  • Shipping conditions: Dry Ice

Target Details

  • Ic50: 20 ÎźM

References

  • Bateman et al. 2009. Bioorg Med Chem Lett. 19(24):6898-901. PMID: 19896844.