Cat. #151624
Anti-EndoPDI [2E7/7]
Cat. #: 151624
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: EndoPDI
Class: Monoclonal
Application: ELISA ; IHC ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Roy Bicknell
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-EndoPDI [2E7/7]
- Research fields: Apoptosis and autophagy;Cancer;Cell signaling and signal transduction
- Clone: 2E7/7
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: CD1
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; IF ; IP ; WB
- Description: Endothelial protein disulfide isomerase (EndoPDI; TXNDC5) is a thioredoxin member of the protein disulfide isomerase family of chaperone proteins. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells.
- Immunogen: Synthesized peptide - 12 amino acids long (ADGEDGQDPHSK) corresponding to residues 52 - 63 of the EndoPDI protein.
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: EndoPDI
- Target background: Endothelial protein disulfide isomerase (EndoPDI; TXNDC5) is a thioredoxin member of the protein disulfide isomerase family of chaperone proteins. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells.
Applications
- Application: ELISA ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Sullivan et al. 2003. J Biol Chem. 278(47):47079-88. PMID: 12963716.
- EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor.
