pTRE/SP S245X w/ 5’UTR vector

Plasmids for the study of hereditary spastic paraplegia

Contributors

Institute
Drexel University
Cat. #: 154342
Tool sub type: pTRE-Tight
Research Fields: Cell biology;Genetics;Neurobiology
Target: spastin
Backbone size without insert: 2600
Bacterial resistance: Ampicillin
Product description: Plasmids for the study of hereditary spastic paraplegia
Additional notes: Plasmids for the study of hereditary spastic paraplegia
References:

Solowska et al. 2017. Mol Biol Cell. 28(13):1728-1737. PMID: 28495799.

Truncating mutations of SPAST associated with hereditary spastic paraplegia indicate greater accumulation and toxicity of the M1 isoform of spastin.

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