pJEK21 Gamma-Synuclein Vector

pJEK21 is a derivative of pET15b with the open reading frame encoding the human gamma-synuclein (Îł-synuclein) cloned in via the NdeI and BamHI restriction sites. In this construct Îł-synuclein is expressed as a fusion protein with an N-terminal six His tag.

Contributors

Inventor Institute
Dr Fiona Benson Lancaster University
Cat. #: 152050
Research Fields: Neurobiology
Product description: pJEK21 is a derivative of pET15b with the open reading frame encoding the human gamma-synuclein (Îł-synuclein) cloned in via the NdeI and BamHI restriction sites. In this construct Îł-synuclein is expressed as a fusion protein with an N-terminal six His tag.
Additional notes: Gamma synuclein is structurally related to alpha-synuclein. Due to these structural similarities, gamma-synuclein can also aggregate in vitro and in vivo. This aggregation is believed to be a crucial trigger of neurodegeneration in alpha-synucleinopathies. Motor neurones express high levels of gamma-synuclein, with the protein highly abundant in their axons, where it might affect organisation of axonal cytoskeleton.
Application notes: pJEK21 is a derivative of pET15b with the open reading frame encoding the human gamma-synuclein (γ-synuclein) cloned in via the NdeI and BamHI restriction sites. In this construct γ-synuclein is expressed as a fusion protein with an N-terminal six His tag.

Related Tools for Vectors

Cat. # Tool Name
152046 pJEK1 Alpha-Synuclein Vector Key Info View Tool
152049 pJEK11 Beta-Synuclein Vector Key Info View Tool
152742 Chicken IgY precipitating protein Vector Key Info View Tool
153458 pRSF-1b-UbcH5B Vector Key Info View Tool
153544 pHyg-AID(31-114) Plasmid Key Info View Tool

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.