pHBx vector

This vector can be used to express hepatitis B virus HBx protein in a variety of primary and cancer cells and provides better detection ability than currently available anti-HBx antibodies.

Contributors

Inventor Institute
Michael Bouchard Drexel University
Cat. #: 156512
Tool sub type: pcDNA3.1
Research Fields: Cancer;Microbiology
Target: HBx
Backbone size without insert: 5428
Bacterial resistance: Ampicillin
Selectable markers: Neomycin
Alternate name: nonstructural protein X, protein X, peptide X, pX
Product description: This vector can be used to express hepatitis B virus HBx protein in a variety of primary and cancer cells.
Application notes: Multi-functional hepatitis B viral protein, non-structural protein X, that modulates mitochondrial function in host hepatocytes interfering with host anti-viral defenses, promoting viral transcription, and contributing to hepatocellular carcinoma development.
Shipping conditions: Dry Ice
References:

Clippinger et al. 2008. J Virol. 82(14):6798-811. PMID: 18448529.

McClain et al. 2007. J Virol. 81(21):12061-5. PMID: 17699583.

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