CancerTools.org offers a wide range of cancer research antibodies including monoclonal, polyclonal and a growing offering of recombinant antibodies for research in DNA damage and repair, proliferation, regulated cell death, cell signalling and adhesion, tumour microenvironment, inflammation and immunophenotyping.
ELISA, WB (natural and recombinant proteines), ICF, IHC, In immunoprecipitation works efficiently and the IP-ed complexes can be eluted with the MDQNNSLPPYAQGLASPQ epitope peptide.
Reactivity:
Human, mouse, xenopus, chicken, zebrafish (does not work on Drososphila)
Cell culture. Resistant cell line models are an essential tool in studying cancer drug resistance mechanisms. The PEO1-OR cell line was used to understand how ovarian cancer cells develop resistance to olaparib. Moreover, The PEO1-OR cell line was used to confirm that combinations of olaparib with the ATR/CHK1 pathway inhibitors act synergistically against ovarian cancer cells. The PEO1-OR cell line can be used to screen for new drugs or drug combinations that can overcome resistance to olaparib and to identify biomarkers associated with drug resistance.
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