Antibody to TATA binding protein, a general transcription factor that binds to the TATA box DNA sequence and is essential for initiating transcription of many genes, including those involved in cancer. Epitope mapping showed that it recognises the first 18 amino acids of human TBP.
| Institute |
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| Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC) |
| Cat. #: | 162429 |
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| Research Fields: | Epigenetics and Nuclear signalling |
| Application: | ELISA, WB (natural and recombinant proteines), ICF, IHC, In immunoprecipitation works efficiently and the IP-ed complexes can be eluted with the MDQNNSLPPYAQGLASPQ epitope peptide. |
| Target: | TBP |
| Reactivity: | Human, mouse, xenopus, chicken, zebrafish (does not work on Drososphila) |
| Clone: | TBP-3G3 |
| Host: | Mouse |
| Class: | Monoclonal |
| Primary citation: | Brou et al. (1993). EMBO J. 12, 489-499. PMID: 8440239 |
| Product description: | Antibody to TATA binding protein, a general transcription factor that binds to the TATA box DNA sequence and is essential for initiating transcription of many genes, including those involved in cancer. Epitope mapping showed that it recognises the first 18 amino acids of human TBP. |
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| Additional notes: | Avoid repeat freezing and thawing cycles. Does not contain any preservative. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1, k |
| Immunogen: | Full length recombinant human TBP as a fusion protein |
| Target background: | TATA-binding protein is a general transcription factor that binds to the TATA box DNA sequence and is essential for initiating transcription of many genes, including those involved in cancer. |
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| Storage conditions: | -20°C (up to 3 years) |
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| References: |
Brou et al. (1993). EMBO J. 12, 489-499, PMID: 8440239 Lescure et al. (1994) EMBO J. 13, 1166-1175, PMID: 7510635 Jordan et al. (1996) J. Cell Biol. 133, 225-234, |
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