Melan-p53-3 cell line

Contributors

Inventor Institute
Elena Sviderskaya St. George's University London
Product description: The melan-p53-1, -2 and -3 cell lines are immortal melanocyte cell lines derived from the skin of neonatal Tp53–/– C57BL/6J mice. The expression of Ink4a in these cells is supressed and Arf expression is diminished. These cells are visibly pigmented and display morphology typical of normal melanocytes and can be useful in studying the role of p53 in melanocytes.
Gender: Male
CRISPR: No
Conditional: No
Cat. #:
Tool sub type: 10XUAS IVS p10
Organism: Mouse
Tissue: Skin
Gender: Male
Model: Immortalised non-cancerous cell lines
Morphology: Small, oval-fusiform
Growth properties: Adherent
Primary citation: Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20;94(6):446-54. PMID: 11904317
Format: Frozen
Storage conditions: liquid N2
Growth medium: RPMI + FBS (10%) + TPA (200 nM) + cholera toxin (CT) (200 pM)
Mycoplasma free: Yes
References:

Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20

94(6):446-54. PMID: 11904318

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