Cat. #157770
Negative control iBody (ATTO488)
Cat. #: 157770
Sub-type: Marker
Availability: 3-4 weeks
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jiri Strohalm ; Karel Ulbich ; Petr Cigler ; Pavel Majer ; Frantisek Sedlak ; Tomas Knedlik ; Jirí Schimer ; Jan Konvalinka ; Pavel Sacha ; Sub Vladlmir ; Jan Tykvart ; Vaclav Navratil
Institute: Institute of Organic Chemistry and Biochemistry ; Charles University ; Institute of Macromolecular Chemistry
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: Negative control iBody (ATTO488)
- Research fields: Cancer
- Tool sub type: Marker
- Description: - iBodies are capable of replacing antibodies in biomedical applications such as ELISA, flow cytometry, confocal microscopy, immunocytochemistry, Western Blot and immunoprecipitation. - These iBodies consist of an N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer decorated with low-molecular-weight compounds that function as targeting ligand (e.g., enzyme inhibitors, receptor ligands), affinity anchor (e.g., biotin) and/or imaging probe (various fluorophores). - These iBodies have been used for enzyme inhibition, protein isolation, immobilization, quantification and live cell imaging as well as for classical Western Blot application. The system is remarkably modular and can be used for different biological/biochemistry assays.
- Purpose: Marker
- Additional notes: HPMA conjugate characteristics: MW: 78 041 g/mol #Biotins/molecule: 8 Fluorochrome name: ATTO488 #Fluorochrome/molecule: 5
Handling
- Storage conditions: Storage at -20° C; solubility H2O; stable at RT, 4° C and -80° C
- Shipping conditions: Dry Ice
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References
- Ĺ imon et al. 2018. ACS Chem Biol. 13(12):3333-3342. PMID: 30489064.
- DvoĹĂĄkovĂĄ et al. 2017. J Med Chem. 60(20):8385-8393. PMID: 28953383.
- Ĺ ĂĄcha et al. 2016. Angew Chem Int Ed Engl. 55(7):2356-60. PMID: 26749427.
