SAR-22-019F mouse line Product

Transgenic mouse with hepatocyte-specific overexpression of MDA-9 (Alb/MDA-9)

Breast cancer Page

[…] grouped into four categories based on the expression of hormone receptors: oestrogen receptor positive (ER +), progesterone receptor positive (PR+), human epidermal growth factor receptor positive (HER2+), and triple-negative (TNBC), which […]

MCF7 S9 Cell Line. Early log phase. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC), UK.

MCF7/S9 Cell Line Product

MCF-7/S9 cell line is an oestrogen-responsive (not oestrogen-dependent) breast cancel model. This model is derived from MCF-7, a human breast carcinoma line with epithelial like morphology. The MCF-7/S9 cell […]

CDK7 inhibitor BS-181 Small Molecule (Tool Compound) Product

[…] is the only other CDK that is inhibited in concentrations lower than 1 M. In MCF-7 cells, BS-181 inhibited the phosphorylation of CDK7 substrates, promoted cell cycle arrest and apoptosis […]