VLS-VSCC cell line

A novel spontaneously immortalized cell line established from vulva squamous cell carcinoma associated with lichen sclerosus

Contributors

Inventor Institute
Daniela Elena Costea ; Harsh Dongre ; Line Bj̙rge Haukeland University Hospital; University of Bergen
Cat. #: 160853
Unit size: 1×10^6 cells / vial
Cancer types: Gynaecologic cancer
Research Fields: Cancer
Organism: Human
Model: Cancer Model
Growth properties: Doubling time: 18.90 Â?„Â… 0.53 hours
Cancer Types In Detail: Vulvar lichen sclerosus and vulva squamous cell carcinoma
Alternate name: UB-VCC1
Product description: A novel spontaneously immortalized cell line established from vulva squamous cell carcinoma associated with lichen sclerosus. Currently, there are no in vitro models to study VSCC-VLS. This is the first cell line modelling this disease.
Conditional: No
Production details: Spontaneously immortalized, i.e without any additional genetic alterations
Cellosaurus ID: CVCL_YD88
disease: Cancer
Format: Frozen
Growth medium: Spontaneously immortalized, i.e without any additional genetic alterations DMEM/Nutrient Mixture F-12 Ham medium (D8437, Sigma) supplemented with 10% NBCS, 1X Insulin-Transferrin-Selenium (41400-04, Thermofisher Scientific), 0.4 ug/mL hydrocortisone (H0888, Sigma), 50ug/mL L-ascorbic acid (A7631, Sigma), and 10ng/mL epidermal growth factor (E9644, Sigma) Doubling time: 18.90 Â?„Â… 0.53 hours
References:

Dongre et al. 2020. Exp Cell Res. 386(1):111684. PMID: 31654625.

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