Melan-p53-3 cell line

Contributors

Inventor Institute
Elena Sviderskaya St. George's University London
Cat. #:
Cancer types: N/A
Research Fields: Tissue-specific biology
Organism: Mouse
Tissue: Skin
Gender: Unspecified
Model: Immortalised non-cancerous cell lines
Morphology: Small, oval-fusiform
Growth properties: Adherent
Primary citation: Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20;94(6):446-54. PMID: 11904317
Product description: The melan-p53-1, -2 and -3 cell lines are immortal melanocyte cell lines derived from the skin of neonatal Tp53–/– C57BL/6J mice. The expression of Ink4a in these cells is supressed and Arf expression is diminished. These cells are visibly pigmented and display morphology typical of normal melanocytes and can be useful in studying the role of p53 in melanocytes.
Gender: Unspecified
CRISPR: No
Conditional: No
disease: Non-cancer
Storage conditions: liquid N2
Growth medium: RPMI + FBS (10%) + TPA (200 nM) + cholera toxin (CT) (200 pM)
Biosafety level: BSL1
References:

Sviderskaya EV, et al. J Natl Cancer Inst. 2002 Mar 20

94(6):446-54. PMID: 11904318

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