#162009

Melan-d1 cell line

Cat. #162009

Melan-d1 cell line

Cat. #: 162009

Organism: Mouse

Tissue: Skin

Disease: Non-cancer

Model: Immortalised non-cancerous cell lines

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Elena Sviderskaya

Institute: St. George's University London

Primary Citation: Evans RD, et al. Curr Biol. 2014 Aug 4;24(15):1743-50. PMID: 25065759

Tool Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Melan-d1 cell line
  • Organism: Mouse
  • Tissue: Skin
  • Disease: Non-cancer
  • Morphology: Small, oval-fusiform
  • Model: Immortalised non-cancerous cell lines
  • Description: The melan-d1 cell line is an immortal melanocyte cell line derived from the skin of neonatal dilute (dl20J) Ink4aArf -/- C57BL6/J mice. The dilute (dl20J) mutation in the myosin Va gene results in perinuclear clustering of pigmented melanosomes. These melanocytes are a useful tool for studies of pigmentation genetics and transport of photoprotective eumelanin
  • Application: Melanocyte cell biology

Applications

  • Application: Melanocyte cell biology

Handling

  • Growth medium: RPMI + FBS (10%) + TPA (200 nM) + cholera toxin (CT) (200 pM)
  • Storage conditions: liquid N2

References

  • Evans RD, et al. Curr Biol. 2014 Aug 4
  • 24(15):1743-50. PMID: 25065760