Cat. #162009
Melan-d1 cell line
Cat. #: 162009
Organism: Mouse
Tissue: Skin
Disease: Non-cancer
Model: Immortalised non-cancerous cell lines
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Elena Sviderskaya
Institute: St. George's University London
Primary Citation: Evans RD, et al. Curr Biol. 2014 Aug 4;24(15):1743-50. PMID: 25065759
Tool Details
*FOR RESEARCH USE ONLY
- Name: Melan-d1 cell line
- Organism: Mouse
- Tissue: Skin
- Disease: Non-cancer
- Morphology: Small, oval-fusiform
- Model: Immortalised non-cancerous cell lines
- Description: The melan-d1 cell line is an immortal melanocyte cell line derived from the skin of neonatal dilute (dl20J) Ink4aArf -/- C57BL6/J mice. The dilute (dl20J) mutation in the myosin Va gene results in perinuclear clustering of pigmented melanosomes. These melanocytes are a useful tool for studies of pigmentation genetics and transport of photoprotective eumelanin
- Application: Melanocyte cell biology
Applications
- Application: Melanocyte cell biology
Handling
- Growth medium: RPMI + FBS (10%) + TPA (200 nM) + cholera toxin (CT) (200 pM)
- Storage conditions: liquid N2
References
- Evans RD, et al. Curr Biol. 2014 Aug 4
- 24(15):1743-50. PMID: 25065760
