Cat. #161967
DuCap 2 [BIC B] CRPC Cell line
Cat. #: 161967
Organism: Human
Tissue: Prostate
Disease: Cancer
Model: Tumour Cell Line
£575.00
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Contributor
Inventor: Wytske van Weerden
Institute: Erasmus University Medical Centre
Primary Citation: Moll JM et al. 2022. Front. Oncol. Jun 13,12:877613. PMID: 35769712
Tool Details
*FOR RESEARCH USE ONLY
- Name: DuCap 2 [BIC B] CRPC Cell line
- Parental cell: DuCap
- Organism: Human
- Tissue: Prostate
- Disease: Cancer
- Model: Tumour Cell Line
- Model description: CRPC model
- Receptors of note: Androgen receptor
- Description: CRPC DuCap cell lines (2 sublines made resistant to Bicalutamide through long-term passaging) - Bicalutamide B. DuCap Bicalutamide was generated by long-term culture of DuCap cells in androgen depleted media with Bicalutamide, an AR antagonist. These cell lines can be used to study the role of AR signalling and mechanisms of resistance to androgen deprivation therapy and AR targeting agents in CRPC. This cell line is subclone B
- Application: Tumour Modelling
Applications
- Application: Tumour Modelling
Handling
- Growth medium: RPMI1640 + 10% DCC-FCS + 1 uM BIC
- Storage conditions: liquid N2
- Cultured in antibiotics: 1% Penicillin/Streptomycin
References
- Moll JM et al. 2022. Front. Oncol. Jun 13,12:877613. PMID: 35769713
