#151823

Anti-TRF2 [SWE38]

Cat. #151823

Anti-TRF2 [SWE38]

Cat. #: 151823

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: human TRF2

Class: Polyclonal

Application: ChIP ; IF ; WB

Reactivity: Human

Host: Rabbit

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Stephen West

Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-TRF2 [SWE38]
  • Research fields: Cancer;Genetics
  • Clone: SWE38
  • Tool sub type: Primary antibody
  • Class: Polyclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Rabbit
  • Application: ChIP ; IF ; WB
  • Description: TRF2 (also known as TERF2), is a component of the telomere nucleoprotein complex. Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes.
  • Immunogen: His tagged full length recombinant TRF2 (from baculovirus)
  • Recommended controls: Hela S1.2.11

Target Details

  • Target: human TRF2
  • Tissue cell line specificity: Hela S1.2.11
  • Target background: TRF2 (also known as TERF2), is a component of the telomere nucleoprotein complex. Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes.

Applications

  • Application: ChIP ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: Whole serum
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Tarsounas et al. 2004. Cell. 117(3):337-47. PMID: 15109494.
  • Telomere maintenance requires the RAD51D recombination/repair protein.
  • Tarsounas et al. 2003. Oncogene. 22(8):1115-23. PMID: 12606939.
  • BRCA2-dependent and independent formation of RAD51 nuclear foci.