Anti-TNFRSF18 (soluble form) [T10P2H9*B9]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-TNFRSF18 (soluble form) [T10P2H9*B9]
• Alternate name: Tumor Necrosis Factor Receptor Superfamily Member 18; Glucocorticoid-Induced TNFR-Related Protein; Activation-Inducible TNFR Family Receptor; AITR; GITR; TNF Receptor Superfamily Activation-Inducible Protein; CD357 Antigen; GITR-D; CD357
• Research fields: Cancer;Cell signaling and signal transduction;Immunology
• Clone: T10P2H9*B9
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Molecular weight: 26 kDa
• Reactivity: Human
• Host: Mouse
• Application: ELISA ; IHC ; WB
• Description: TNFRSF18 is a type I transmembrane protein with homology to members of divergent costimulatory molecules in the TNFRSF. To date three isoforms of TNFRSF18 have been identified, including one soluble form that lacks a transmembrane domain. According to homology of the cytoplasmic domain, TNFRSF18 and other three TNFRSF members (4–1BB, CD27, and OX40) probably constitute a new subfamily as divergent costimulators. TNFRSF18 and the other subfamily members bind TRAF molecules and activate NF-KB.
• Immunogen: Ovalbumin conjugated peptide - PWQQKWVQE
• Isotype: IgG1 kappa
• Recommended controls: IHC- formalin-fixed, paraffin-embedded breast cancer sections; WB - Jurkat cell lysates

Target Details

• Target: Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18-soluble form), GITR
• Molecular weight: 26 kDa
• Tissue cell line specificity: IHC- formalin-fixed, paraffin-embedded breast cancer sections; WB - Jurkat cell lysates
• Target background: TNFRSF18 is a type I transmembrane protein with homology to members of divergent costimulatory molecules in the TNFRSF. To date three isoforms of TNFRSF18 have been identified, including one soluble form that lacks a transmembrane domain. According to homology of the cytoplasmic domain, TNFRSF18 and other three TNFRSF members (41BB, CD27, and OX40) probably constitute a new subfamily as divergent costimulators. TNFRSF18 and the other subfamily members bind TRAF molecules and activate NF-KB.

Applications

• Application: ELISA ; IHC ; WB

Handling

• Format: Liquid
• Concentration: 0.9-1.1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -15° C to -25° C
• Shipping conditions: Dry ice

Related Tools

• Related tools: Anti-TNFRSF18(r) [T9P4G4*D7] ; Anti-TNFRSF18 (soluble form), Recombinant [T10P2H9*B9]