Anti-TLT-1 [4.8]monoclonal antibody

These rabbit hybridoma cells produce a monoclonal antibody to The membrane receptor Triggering Receptors Expressed on Myeloid cells (TREM)- like transcript-1 (TLT-1), located on alpha-granules of platelets.

Contributors

Inventor Institute
Anthony Valance Washington University of Puerto Rico
Cat. #: 160704
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cell biology
Application: WB ; IP
Target: Triggering Receptors Expressed on Myeloid cells (TREM)- like transcript-1 (TLT-1)
Reactivity: Mouse
Host: Rabbit
Class: Monoclonal
Product description: Mouse anti-TLT-1 (clone 4.8) monoclonal antibody. These rabbit hybridoma cells produce a monoclonal antibody to The membrane receptor Triggering Receptors Expressed on Myeloid cells (TREM)- like transcript-1 (TLT-1), located on alpha-granules of platelets. TREM-like transcript-1 (TLT-1) is involved in thrombus formation and platelet aggregation, inflammatory modulation, immune responses. Members of the TREM family are key regulators of innate and adaptive immune responses. According to Manfredi, et al., 2018, murine TLT-1 share a 65% identity with human TLT-1 and have been used to support existing clinical data that enable a better understanding of thrombotic and inflammatory diseases.
Conjugation: Unconjugated
Immunogen: Rabbits were immunized with the negatively charged region of the mTLT-1 extracellular domain 122PPVPGPREGEEAEDEK139.
Target background: These rabbit hybridoma cells produce a monoclonal antibody to The membrane receptor Triggering Receptors Expressed on Myeloid cells (TREM)- like transcript-1 (TLT-1), located on alpha-granules of platelets. TREM-like transcript-1 (TLT-1) is involved in thrombus formation and platelet aggregation, inflammatory modulation, immune responses. Members of the TREM family are key regulators of innate and adaptive immune responses. According to Manfredi, et al., 2018, murine TLT-1 share a 65% identit…
Format: Liquid
Shipping conditions: Dry ice
References:

Manfredi et al. 2018. Monoclon Antib Immunodiagn Immunother. 37(2):78-86. PMID: 29708866.

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