This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection.
| Inventor | Institute |
|---|---|
| Geoff Toms | Newcastle University |
| Cat. #: | 151639 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Microbiology |
| Application: | IF ; ELISA ; IHC; IF ; WB |
| Target: | Respiratory syncytial virus subgroup A G glycoprotein |
| Reactivity: | Virus |
| Clone: | 133 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Identification and location of expression of the G glycoprotein of HRSV of both sub-groups A and B . This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Human RSV strain A2 infected HeLa cells |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | Identification and location of expression of the G glycoprotein of HRSV of both sub-groups A and B . This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | RPMI + 10% FCS + Hepes (25mM) + glutamine (2mM) |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Vanover et al. 2017. Nat Commun. 8(1):667. PMID: 28939853. Shi et al. 2016. Sci Rep. 6:35851. PMID: 27767097. Robinson et al. 2014. J Med Virol. 86(7):1267-77. PMID: 24415460. Generation and epitope mapping of a sub-group cross-reactive anti-respiratory syncytial virus G glycoprotein monoclonal antibody which is protective in vivo. |
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