Mammalian PITP?Ÿ (phosphatidylinositol transfer protein ?Ÿ) is a 272-amino-acid polypeptide capable of transferring PtdIns, PtdCho and SM (sphingomyelin) between membrane bilayers. Ablation of PITP?Ÿ is embryonically lethal. This antibody is specific for both splice variants of PITP?Ÿ but does not recognise PITPa despite the 95% similarity between the two.
| Inventor | Institute |
|---|---|
| Shamshad Cockcroft | University College London (UCL) |
| Cat. #: | 151819 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction |
| Application: | ELISA ; IF ; IP ; WB |
| Target: | Rat PITPb |
| Reactivity: | Dog ; Human ; Mouse ; Rat |
| Clone: | 4a7 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | Mammalian PITP?ĂÂ (phosphatidylinositol transfer protein ?ĂÂ) is a 272-amino-acid polypeptide capable of transferring PtdIns, PtdCho and SM (sphingomyelin) between membrane bilayers. Ablation of PITP?ĂÂ is embryonically lethal. This antibody is specific for both splice variants of PITP?ĂÂ but does not recognise PITPa despite the 95% similarity between the two. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Immunogen: | Whole Rat PITPb protein |
| Target background: | Mammalian PITP?ĂÂ (phosphatidylinositol transfer protein ?ĂÂ) is a 272-amino-acid polypeptide capable of transferring PtdIns, PtdCho and SM (sphingomyelin) between membrane bilayers. Ablation of PITP?ĂÂ is embryonically lethal. This antibody is specific for both splice variants of PITP?ĂÂ but does not recognise PITPa despite the 95% similarity between the two. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1mg/ml |
| Storage buffer: | RPMI 1640 + 10% FCS + 2mM L-glutamine + penicillin/streptomycin |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Carvou et al. 2010. J Cell Sci. 123:1262-73. PMID: 20332109 Shadan et al. 2008. Traffic. 9:1743-56. PMID: 18636990 Morgan et al. 2006. Biochem J. 398:411-21. PMID: 16780419 |
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