Cdc20 is phosphorylated during mitosis so this epitope is a good marker of cell cycle progression
| Inventor | Institute |
|---|---|
| Julian Gannon | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| Cat. #: | 151753 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | ELISA ; WB |
| Target: | cdc20 |
| Reactivity: | Xenopus laevis |
| Clone: | BT2.1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | APC/C activator protein CDC2; Cell division control protein 2; YGL116W; Cell Division Cycle 2; P55CDC; CDC2 Cell Division Cycle 2 Homolog; Cell Division Cycle 2 Homolog; BA276H19.3; CDC2A |
|---|---|
| Product description: | Cdc20 (fizzy protein) is associated with the activation of the anaphase-promoting complex at the onset of anaphase. Cdc20 is phosphorylated during mitosis so this epitope is a good marker of cell cycle progression |
| Conjugation: | Unconjugated |
| Isotype: | Not Known |
| Molecular weight: | 55 kDa |
| Immunogen: | GPKMQGpTPSRAG. pT represents phosphorylated Thr79. |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | Cdc20 (fizzy protein) is associated with the activation of the anaphase-promoting complex at the onset of anaphase. Cdc20 is phosphorylated during mitosis so this epitope is a good marker of cell cycle progression |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Labit et al. 2012. EMBO J. 31(15):3351-62. PMID: 22713866. Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C. |
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