Cat. #151378
Anti-LILRB1 [VMP55]
Cat. #: 151378
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Leukocyte Immunogolobulin-like Receptor subfamily B member 1 (LILRB1, CD85)
Class: Monoclonal
Application: FACS ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Karen Pulford
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-LILRB1 [VMP55]
- Research fields: Immunology
- Clone: VMP55
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 120 kDa
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IP ; WB
- Description: LILRB1 is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. The functional role of LILRB1 has not been fully elucidated.
- Immunogen: Hairy cell leukaemia cells
- Isotype: IgG1 kappa
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Leukocyte Immunogolobulin-like Receptor subfamily B member 1 (LILRB1, CD85)
- Molecular weight: 120 kDa
- Tissue cell line specificity: Mouse
- Target background: LILRB1 is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. The Fn role of LILRB1 has not been fully elucidated.
Applications
- Application: FACS ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Lamar et al. 2010. Blood. 115(16):3278-86. PMID: 20194892.
- Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages.
- Prod'homme et al. 2007. J Immunol. 178(7):4473-81. PMID: 17372005.
- The human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells.
- Banham et al. 1999. J Leukoc Biol. 65(6):841-5. PMID: 10380908.
- Identification of the CD...