#151378

Anti-LILRB1 [VMP55]

Cat. #151378

Anti-LILRB1 [VMP55]

Cat. #: 151378

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Leukocyte Immunogolobulin-like Receptor subfamily B member 1 (LILRB1, CD85)

Class: Monoclonal

Application: FACS ; IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Karen Pulford

Institute: University of Oxford

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-LILRB1 [VMP55]
  • Research fields: Immunology
  • Clone: VMP55
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Molecular weight: 120 kDa
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IP ; WB
  • Description: LILRB1 is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. The functional role of LILRB1 has not been fully elucidated.
  • Immunogen: Hairy cell leukaemia cells
  • Isotype: IgG1 kappa
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Leukocyte Immunogolobulin-like Receptor subfamily B member 1 (LILRB1, CD85)
  • Molecular weight: 120 kDa
  • Tissue cell line specificity: Mouse
  • Target background: LILRB1 is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. The Fn role of LILRB1 has not been fully elucidated.

Applications

  • Application: FACS ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Lamar et al. 2010. Blood. 115(16):3278-86. PMID: 20194892.
  • Promoter choice and translational repression determine cell type-specific cell surface density of the inhibitory receptor CD85j expressed on different hematopoietic lineages.
  • Prod'homme et al. 2007. J Immunol. 178(7):4473-81. PMID: 17372005.
  • The human cytomegalovirus MHC class I homolog UL18 inhibits LIR-1+ but activates LIR-1- NK cells.
  • Banham et al. 1999. J Leukoc Biol. 65(6):841-5. PMID: 10380908.
  • Identification of the CD...