Cat. #151485
Anti-Integrin a2 [HAS-6]
Cat. #: 151485
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Integrin alpha 2 subunit (CD49b)
Class: Monoclonal
Application: FACS ; IHC ; IP
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Fiona Watt
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Integrin a2 [HAS-6]
- Research fields: Cancer;Cell biology;Cell signaling and signal transduction;Metabolism
- Clone: HAS-6
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Host: Mouse
- Application: FACS ; IHC ; IP
- Description: Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. Integrin alpha II combines with Integrin beta 1 to form the alpha2/beta1 integrin duplex. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Integrin alpha 2 subunit (CD49b)
- Target background: Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. Integrin alpha II combines with Integrin beta 1 to form the alpha2/beta1 integrin duplex. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
Applications
- Application: FACS ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Sugiyama et al. 1993. Carcinogenesis. 14(10):2171-6. PMID: 7693359.
- Comparison of integrin expression and terminal differentiation capacity in cell lines derived from oral squamous cell carcinomas.
- Tenchini et al. 1993. Cell Adhes Commun. 1(1):55-66. PMID: 7521749.
- Evidence against a major role for integrins in calcium-dependent intercellular adhesion of epidermal keratinocytes.
