Cat. #158053
Anti-IgT
Cat. #: 158053
Unit size: 100 ug
Availability: 10-12 weeks
Target: Immunoglobulin T (IgT)-heavy chain
Class: Polyclonal
Application: ELISA
Reactivity: Grass Carp
Host: Rabbit
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Abdo Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-IgT
- Research fields: Cell biology;Immunology
- Class: Polyclonal
- Conjugation: Unconjugated
- Molecular weight: 65
- Reactivity: Grass Carp
- Host: Rabbit
- Application: ELISA
- Description: Teleost IgT is specialised in gut mucosal immunity. IgT is present in serum as monomers, whereas in the gut mucus it forms mainly noncovalent multimers similar in mass to IgM. In fish, IgT+ B cells have been identified in several species and constitute around 51% of all B cells in the intestinal mucosa. Consistent with the prevalent roles of IgT in gut immunity, most bacteria in the gut lumen are coated with IgT, and IgT responses to gut parasites are measurable only in the gut, whereas IgM responses are detected only in serum. This anti-IgT antibody may provide a useful tool to monitor vaccine performance in fish and will assist in the development of future vaccines. Anti-IgT antibody may provide a useful tool to monitor mucosal-based vaccine performance in fish and will assist in the development of future vaccines.
- Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved in carp species.
- Recommended controls: ELISA: peptide immunogen
Target Details
- Target: Immunoglobulin T (IgT)-heavy chain
- Molecular weight: 65
- Target background: Teleost IgT is specialised in gut mucosal immunity. IgT is present in serum as monomers, whereas in the gut mucus it forms mainly noncovalent multimers similar in mass to IgM. In fish, IgT+ B cells have been identified in several species and constitute around 51% of all B cells in the intestinal mucosa. Consistent with the prevalent roles of IgT in gut immunity, most bacteria in the gut lumen are coated with IgT, and IgT responses to gut parasites are measurable only in the gut, whereas IgM responses are detected only in serum. This anti-IgT antibody may provide a useful tool to monitor vaccine performance in fish and will assist in the development of future vaccines. Anti-IgT antibody may provide a useful tool to monitor mucosal-based vaccine performance in fish and will assist in the development of future vaccines.
Applications
- Application: ELISA
Handling
- Format: Liquid
- Unit size: 100 ug
- Storage buffer: Unpurified anti-serum from rabbit preserved in 0.02% Thiomersal
- Shipping conditions: Shipping at 4° C
