Cat. #157718
Anti-GTP [2A4]
Cat. #: 157718
Sub-type: Primary antibody
Unit size: 100 ug
Target: GTP
Class: Recombinant
Application: ELISA ; FACS ; IF
Reactivity: Human
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Urpo Lamminmäki
Institute: University of Turku
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-GTP [2A4]
- Research fields: Cancer;Metabolism
- Tool sub type: Primary antibody
- Class: Recombinant
- Conjugation: Unconjugated
- Reactivity: Human
- Application: ELISA ; FACS ; IF
- Description: GTPases are central cellular signaling proteins, which cycle between a GDP-bound inactive and a GTP-bound active conformation in a controlled manner. Ras GTPases are frequently mutated in cancer and so far only few experimental inhibitors exist. The most common methods for monitoring GTP hydrolysis rely on luminescent GDP- or GTP-analogs. (From Kopra et al Anal. Chem. 2015)
Target Details
- Target: GTP
- Target background: GTPases are central cellular signaling proteins, which cycle between a GDP-bound inactive and a GTP-bound active conformation in a controlled manner. Ras GTPases are frequently mutated in cancer and so far only few experimental inhibitors exist. The most common methods for monitoring GTP hydrolysis rely on luminescent GDP- or GTP-analogs. (From Kopra et al Anal. Chem. 2015, 87, 6, 35273534)
Applications
- Application: ELISA ; FACS ; IF
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
Related Tools
- Related tools: Anti-GTP [3A5] recombinant antibody
References
- Kopra et al. 2017. Anal Chem. 89(8):4508-4516. PMID: 28318223.
- Kopra et al. 2015. Anal Chem. 87(6):3527-34. PMID: 25707436.
