FZR1 is related to Fizzy protein (Cdc20). Both FZR1 and Cdc20 are activators of the anaphase promoting complex (APC), which is responsible for the destruction of many cell cycle related proteins.
| Inventor | Institute |
|---|---|
| Julian Gannon | Cancer Research UK, London Research Institute: Clare Hall Laboratories |
| Cat. #: | 151251 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Biochemistry;Cell biology |
| Application: | ELISA ; WB |
| Target: | Fizzy Related Protein (FZR1, Cdh1) |
| Reactivity: | Human ; Mouse |
| Clone: | AR38.2 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Fizzy/Cell Division Cycle 2 Related 1; CDC2-Like Protein 1; Cdh1/Hct1 Homolog; CDC2 Homolog 1; HCDH1; CDH1; FZR; CDC2-Like 1b; KIAA1242; CDC2C; FZR2; HCDH; FYR |
|---|---|
| Product description: | FZR1 is related to Fizzy protein (Cdc20). Both FZR1 and Cdc20 are activators of the anaphase promoting complex (APC), which is responsible for the destruction of many cell cycle related proteins. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | His-tagged recombinant Fizzy Related Protein (also known as Cdh1) |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | FZR1 is related to Fizzy protein (Cdc20). Both FZR1 and Cdc20 are activators of the anaphase promoting complex (APC), which is responsible for the destruction of many cell cycle related proteins. |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Holt et al. 2010. Development. 137(8):1297-304. PMID: 20223764. Spatial regulation of APCCdh1-induced cyclin B1 degradation maintains G2 arrest in mouse oocytes. |
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