Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells. Although FDCs have a very dendritic morphology they are not dendritic cells and FDCs […]
| Inventor | Institute |
|---|---|
| Margaret Goodall | University of Birmingham |
| Cat. #: | 153220 |
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| Unit size: | 100 ug |
| Research Fields: | Cell biology;Immunology |
| Application: | IHC |
| Target: | Dendritic cells |
| Reactivity: | Human |
| Clone: | BU58 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | DC;APC;antigen presenting cells; |
|---|---|
| Product description: | Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells. Although FDCs have a very dendritic morphology they are not dendritic cells and FDCs are not derived from bone-marrow haematopoietic stem cells. |
| Conjugation: | Unconjugated |
| Isotype: | IgM |
| Immunogen: | B lymphoblastoid cell line: HFB1 |
| Target background: | Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells. Although FDCs have a very dendritic morphology they are not dendritic cells and FDCs are not derived from bone-marrow haematopoietic stem cells. |
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| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Johnson et al. 1986. Clin Exp Immunol. 64(1):205-13. PMID: 3524917. |
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